Research Article

Tempol, a Membrane-Permeable Radical Scavenger, Exhibits Anti-Inflammatory and Cardioprotective Effects in the Cerulein-Induced Pancreatitis Rat Model

Table 1

Histological findings in the pancreas observed in rats with or without cerulein and treated with saline or tempol.

Edema
(0–3)
Vacuolisation
(0–3)
Infiltration
(0–3)
Necrosis
(0–3)

Control0 (0-0)0 (0-0)0 (0-0)0 (0-0)
Tempol0 (0-0)0 (0-0)0 (0-0)0 (0-0)
Cerulein2.5 (2-3)2.5 (1–3)2 (1–3)1 (0–2)
Tempol + cerulein2 (1-2)1 (1-2)1 (0–2)0 (0-1)

Median scores with ranges (min–max) of the results on 6 animals in each group are shown. versus control, versus cerulein alone (analysis of variance followed by the Kruskal-Wallis test).