Ameliorative Effects of Antioxidants on the Hippocampal Accumulation of Pathologic Tau in a Rat Model of Blast-Induced Traumatic Brain Injury

Figure 2

Tau accumulates in the soma of hippocampal cells in response to bTBI seven days after blast exposure. Some Tau-1-positive cells (arrows in (b)) exhibited colabeling with the oligodendrocyte-specific protein antibody (OSPA, arrows in (a) and (d)) in blast-exposed rats, while some oligodendrocytes were not colabeled with the Tau-1 antibody (arrowheads in (a) and (d)). The scale bar in (d) = 5 μm for (a)–(d).

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