Screening SIRT1 Activators from Medicinal Plants as Bioactive Compounds against Oxidative Damage in Mitochondrial Function

Figure 2

LC-MS results of SIRT1 activation. LC-MS chromatograms in negative ion mode and structures of (a) substrate TPE-GK(Ac)YDD and (b) deacetylated product TPE-GKYDD. (c) Area of deacetylated product in LC-MS chromatogram. SIRT1 was incubated with or without ginsenoside Rb₂ (Rb₂), ginsenoside F1 (F1), ginsenoside Rc (Rc), and schisandrin A (Sch A). Each bar represented the mean ± SD of triplicate experiments. Compared with control group, .

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(b)

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