Role of Endogenous Sulfur Dioxide in Regulating Vascular Structural Remodeling in Hypertension

<div>Mechanisms by which SO<sub>2</sub> attenuates VSR. SO<sub>2</sub> attenuates VSR by inhibiting proliferation of VSMCs, promoting apoptosis, inhibiting the synthesis of extracellular collagen, promoting the degradation of extracellular collagen, and increasing the antioxidative capacity. SO<sub>2</sub>: sulfur dioxide; VSMCs: vascular smooth muscle cells; ECM: extracellular matrix; ROS: reactive oxygen species.</div>

Oxidative Medicine and Cellular Longevity

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Figure 2

Figure 2: Role of Endogenous Sulfur Dioxide in Regulating Vascular Structural Remodeling in Hypertension 