The Analgesic Effect of the Mitochondria-Targeted Antioxidant SkQ1 in Pancreatic Inflammation

Figure 8

Evoked pain-related behavior measured by Von Frey’s hairs in chronic pancreatitis: while baseline measurements did not differ significantly (a), mice with pancreatitis developed significantly increased pain scores after 4 weeks when compared to the saline controls (b). After 8 weeks of pancreatitis and 8 weeks of treatment, the SkQ1-treated mice show significantly less pain-related behavior than the untreated controls (c + d). Statistically significant results ().

(a) Baseline

(b) 4 weeks

(c) 8 weeks

(d) Cumulative (8 weeks)