Anti-Inflammatory Therapy Modulates Nrf2-Keap1 in Kidney from Rats with Diabetes

Figure 4

Representative immunofluorescence photomicrographs for Nrf2 in renal cortex show the presence of FITC (green) reactivity in the untreated diabetic group tubular epithelial cells cytoplasm, mainly in the proximal tubule brush border (a), and the change in its localization to the nucleus in the diabetic MMF-treated group tubular cells (b). Nuclear counterstaining with DAPI in blue. Original magnification 200x/1.6 zoom.

(a)

(b)