Research Article

PON-1 Activity and Plasma 8-Isoprostane Concentration in Patients with Angiographically Proven Coronary Artery Disease

Table 3

8-Iso-PGF2α concentration according to serum arylesterase and paraoxonase activity quartiles.

Paraoxonase (PONase) [U/L]Arylesterase (AREase) [kU/L]
Quartile 1Quartile 2Quartile 3 Quartile 4 Quartile 1Quartile 2Quartile 3 Quartile 4

All subjects
 Range<9898–135135–224≥225<8787–107107–122≥123
 8-Iso-PGF2α
 [pg/mL]
134 (130–196)114 (89–157)103 (74–146)104 (69–154)140 (100–200)103 (70–162)117 (74–148)118 (83–168)
CAD+
 Range<9898–123123–192≥193<8383–103103–123≥123
 8-Iso-PGF2α
  [pg/mL]
145 (88–158)113 (78–161)112 (88–158)123 (84–169)142 (103–205)122 (89–184)121 (75–157)114 (76–168)
CAD−
 Range<112112–201201–271≥272<9898–108108–130≥130
 8-Iso-PGF2α
  [pg/mL]
124 (70–170)92 (49–125)92 (74–130)110 (71–137)133 (80–153)95 (69–133)103 (74–119)92 (72–149)

8-Iso-PGF2α concentrations are presented as median (25th and 75th percentiles); compared with Quartile 1; CAD+ patients with coronary artery disease and CAD− patients with negative result of coronary angiography.