PON-1 Activity and Plasma 8-Isoprostane Concentration in Patients with Angiographically Proven Coronary Artery Disease

Table 4

Concentration of 8-iso-PGF2α and PONase and AREase activity in patients with and without traditional risk factors.

	8-Iso-PGF2α [pg/mL]	value	Paraoxonase (PONase) [U/L]	value	Arylesterase (AREase) [kU/L]	value
Hypertension/nonhypertension
All subjects	122 (80–170)/101 (79–137)	0.124	125 (93–202)/186 (104–234)	0.065	105 ± 26/112 ± 24	0.159
CAD+	134 (94–195)/101 (78–141)	0.045	121 (89–177)/152 (100–233)	0.501	102 ± 20/110 ± 26	0.218
CAD−	95 (69–138)/112 (80–133)	0.295	183 (99–272)/210 (201–311)	0.484	113 ± 23/114 ± 23	0.841
Diabetes/nondiabetes
All subjects	120 (74–162)/116 (80–163)	0.894	104 (65–163)/153 (102–240)	<0.001	105 ± 25/108 ± 26	0.827
CAD+	126 (100–164)/120 (89–178)	0.694	104 (69–176)/125 (99–202)	0.049	102 ± 26/104 ± 23	0.761
CAD−	110 (71–119)/95 (72–135)	0.293	116 (64–140)/227 (127–306)	0.004	115 ± 25/115 ± 23	0.704
Smoking/nonsmoking
All subjects	126 (89–178)/113 (70–137)	0.006	123 (93–201)/182 (109–264)	0.012	102 ± 26/112 ± 24	0.044
CAD+	140 (89–198)/116 (73–141)	0.042	131 (90–225)/119 (88–191)	0.074	99 ± 26/108 ± 24	0.153
CAD−	117 (90–138)/89 (66–133)	0.223	163 (96–238)/228 (140–300)	0.073	114 ± 20/117 ± 24	0.680

Values are presented as mean ± SD or as median (25th and 75th percentiles). Student’s -test; Mann-Whitney test.