Research Article

Low-Dose Methylmercury-Induced Apoptosis and Mitochondrial DNA Mutation in Human Embryonic Neural Progenitor Cells

Table 5

Specific point mutations of D-Loop gene found after treatment with MeHg in hNPCs.

GroupGene siteMutation type

0 nmol/L349:350ins (C)
378del(A)
382:383ins (C)
387del(C)
444:445ins (A)

10 nmol/L302
353:354del(CC)
372:373del(TA)
378del(C)
385del(A)
403ins (T)
410
413
493
505del(C)
16125

50 nmol/L123
246:247ins (TG)
324del(C)
384del(A)
394:395del(CA)
397
424:425del(TA)
430
440del(A)
442
457
469del(C)
478del(A)
490:491del(AC)
493