Research Article

Changes in Oxidative Stress and Antioxidant Enzyme Activities in Streptozotocin-Induced Diabetes Mellitus in Rats: Role of Alhagi maurorum Extracts

Table 1

Changes in levels of liver function markers, blood glucose levels, and lipid profile in plasma of diabetic rats treated with either water or ethanolic extract of Alhagi maurorum.

ParametersAnimals treatments
Control STZ-groupSTZ-WE-groupSTZ-EE-group

AST (U/L)18.67 ± 1.41503.46 ± 29.6124.33 ± 2.6221.57 ± 1.23
ALT (U/L)6.141 ± .079103.63 ± 12.5639.64 ± 1.4798.62 ± 1.216
Bilirubin (mg/dL)0.51 ± 0.036.982 ± .180.43 ± 0.040.72 ± 0.04
Cholesterol (mg/dL)104.76 ± 7.6203.14 ± 9.0363.92 ± 4.7690.47 ± 7.90
LDL-C (mg/dL)83.58 ± 7.01173.18 ± 8.4754.60 ± 6.4156.51 ± 4.88
HDL-C (mg/dL)88.26 ± 8.1540.246 ± 1.77473.965 ± 6.92763.499 ± 7.549
LDL/HDL ratio1.1 ± 0.144.35 ± 0.230.76 ± 0.080.99 ± 0.13
VLDL-C (mg/dL)24.37 ± 2.1597.52 ± 12.5110.14 ± 1.6016.70 ± 2.24
Triglyceride (mg/dL)121.83 ± 10.7487.60 ± 62.5750.68 ± 8.0283.52 ± 11.21
Glucose (mg/dL) 90.81 ± 5.36437.6 ± 14.10106.83 ± 8.5782.24 ± 7.09

Values are expressed as mean ± SE of 10 rats in each group.
Mean values within a row not sharing the same superscript letters were significantly different, .