Review Article

Role of Antioxidants and Natural Products in Inflammation

Table 1

List of free radicals and their reactivity.

No.Free radicalsReactivity

1Superoxide anionGenerated in mitochondria, cardiovascular system, and other cell types
2Hydrogen peroxideFormed in the human body by a large number of reactions and yields potent reactive species
3Hydroxyl radicalHighly reactive and generated during iron overload and such conditions in the human body
4Peroxyl radicalReactive and formed from lipids, proteins, DNA, and sugar molecules during oxidative damage
5Nitric oxideNeurotransmitter and blood pressure regulation and can yield potent oxidants during pathological states
6PeroxynitriteHighly reactive and formed from NO and superoxide
7OzonePresent as an atmospheric pollutant and can react with various molecules