Low-Dose Aronia melanocarpa Concentrate Attenuates Paraquat-Induced Neurotoxicity

Figure 2

Low-dose AB decreases PQ-induced increase in levels. NG108-15 cells were treated with 50 μM PQ with various doses of AB. AB was added 24 hours prior to PQ; cells were analyzed 48 hours after PQ administration. (a) Total cellular levels measured by dihydroethidium (DHE) oxidation and flow cytometry. . (b) Mitochondrial-specific levels measured by MitoSOX oxidation and flow cytometry. MFI = mean fluorescence intensity. . versus No AB; versus PQ-No AB.

(a)

(b)