Does the Interdependence between Oxidative Stress and Inflammation Explain the Antioxidant Paradox?

Figure 2

Overview of interdependence between oxidative stress and inflammation. When oxidative stress appears as a primary disorder inflammation develops as a secondary disorder and further enhances oxidative stress. On the other hand, inflammation as a primary disorder can induce oxidative stress as a secondary disorder which can further enhance inflammation. NF-κB, nuclear factor-κB; ROS, reactive oxygen species.