The Cellular Response to Oxidatively Induced DNA Damage and Polymorphism of Some DNA Repair Genes Associated with Clinicopathological Features of Bladder Cancer

Table 5

The frequency of individuals with increased lymphocyte sensitivity to DNA damage in various study groups.

Study groups	Proportion of sensitive subjects (%) with respect to
	Basal DNA damage	H2O2-induced DNA damage		Total
		Initial level	Residual level
BC patients ( = 40)	17.5	50^a	10	62.5^b
Individuals older than 60 years ( = 15)	20.0	26.67	26.67	46.67
Individuals with chronic inflammatory diseases ( = 15)	6.67	26.67	6.67	46.67
Controls ( = 35)	8.57	14.29	5.71	40.0

Significant differences were revealed between all the groups by criterion ( = 0.009) and between the case group and controls ( = 0.001).
^bSignificant differences were observed between BC patients and controls ( = 0.05).