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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 5806057, 6 pages
http://dx.doi.org/10.1155/2016/5806057
Review Article

Molecular Hydrogen Therapy Ameliorates Organ Damage Induced by Sepsis

Department of Critical Care Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China

Received 18 February 2016; Revised 25 April 2016; Accepted 25 May 2016

Academic Editor: Xiao-Kang Li

Copyright © 2016 Yijun Zheng and Duming Zhu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Since it was proposed in 2007, molecular hydrogen therapy has been widely concerned and researched. Many animal experiments were carried out in a variety of disease fields, such as cerebral infarction, ischemia reperfusion injury, Parkinson syndrome, type 2 diabetes mellitus, metabolic syndrome, chronic kidney disease, radiation injury, chronic hepatitis, rheumatoid arthritis, stress ulcer, acute sports injuries, mitochondrial and inflammatory disease, and acute erythema skin disease and other pathological processes or diseases. Molecular hydrogen therapy is pointed out as there is protective effect for sepsis patients, too. The impact of molecular hydrogen therapy against sepsis is shown from the aspects of basic vital signs, organ functions (brain, lung, liver, kidney, small intestine, etc.), survival rate, and so forth. Molecular hydrogen therapy is able to significantly reduce the release of inflammatory factors and oxidative stress injury. Thereby it can reduce damage of various organ functions from sepsis and improve survival rate. Molecular hydrogen therapy is a prospective method against sepsis.