Fibroblast Growth Factor-9 Activates c-Kit Progenitor Cells and Enhances Angiogenesis in the Infarcted Diabetic Heart

Figure 5

FGF-9 enhances vessel formation in postinfarcted nondiabetic and diabetic hearts. (a) Representative Masson’s trichrome stained myocardial images for all control and experimental groups depicting blood vessels as indicated by the black arrows. (b) Data suggest that, following MI, the total number of vessels in the infarcted heart is significantly decreased whereas, following FGF-9 treatment, the total number of vessels is significantly increased relative to the MI group for both C57BL/6 and db/db mice. versus sham and versus MI.

(a)

(b)