Mitochondrial Alterations in Peripheral Mononuclear Blood Cells from Alzheimer’s Disease and Mild Cognitive Impairment Patients

Figure 5

PGC-1α and TFAM protein levels in PBMCs derived from AD, MCI patients and healthy controls. PGC-1α (a) and TFAM (b) expression was measured by ELISA in protein extracts derived from PBMCs. The values are expressed as ng of protein and are referred to as specific standard curves. Data was expressed as median ± SEM. The statistical significance was represented by the asterisks as follows: ; ; versus the corresponding control group.

(a)

(b)