Mitochondrial Alterations in Peripheral Mononuclear Blood Cells from Alzheimer’s Disease and Mild Cognitive Impairment Patients

Table 1

Demographic and clinical characteristics of subjects/patients used in the study.

(a) Spanish cohort

	CTL	MCI	AD
(M; F)	30 (16; 14)	24 (14; 10)	20 (8; 12)
Mean age ± SD (years)	71 ± 8	73 ± 6	74 ± 7
MMSE	29 ± 1	27 ± 2	24 ± 3
CDR	0	0.5	1
Disease onset		71.7 ± 6.49	71.67 ± 8.27
LOI (months)		24.5 ± 14.36	26.8 ± 13.25

(b) Italian cohort

	CTL	MCI	AD
(M; F)	248 (116; 131)	70 (44; 26)	276 (99; 177)
Mean age ± SD (years)	75 ± 9.98	71 ± 8.71	78.23 ± 7.37
MMSE	29 ± 1	25.3 ± 4.45	15.1 ± 6.23
CDR	0	0.52 ± 0.06	2 ± 1
Disease onset		69.6 ± 6.2	72.5 ± 7.5
LOI (months)		30.2 ± 12.3	43 ± 31

AD: Alzheimer’s disease; CTL: control; F: female; M: male; MMSE: Mini-Mental State Examination; CDR: Clinical Dementia Rating; LOI: length of illness; and : number. Data are expressed as mean ± SD.