A Case-Control Study of Involvement of Oxidative DNA Damage and Alteration of Antioxidant Defense System in Patients with Basal Cell Carcinoma: Modulation by Tumor Removal

Table 1

Demographics and clinical characteristics of controls subjects and BCC patients.

Characteristics	Control; ()	Cases; ()	value
Demographic
Age (years)	64.71 ± 10.58	66.82 ± 11.59	0.714
Gender, (%)
Male	13 (54.20)	9 (37.5)	0.247
Female	11 (45.8)	15 (62.5)
BMI (kg/m^2)	23.41 ± 2.38	22.98 ± 3.31	0.217
Clinical characteristics
Glucose (mg/dL)	95.82 ± 12.24	101.65 ± 14.10	0.317
BUN (mg/dL)	13.44 ± 3.82	14.32 ± 5.09	0.891
Creatinine (mg/dL)	1.04 ± 0.23	1.05 ± 0.25	0.949
Cholesterol (mg/dL)	187.97 ± 36.44	201.76 ± 34.21	0.402
Triglyceride (mg/dL)	129.64 ± 62.23	109.76 ± 43.34	0.156
HDL-Chol (mg/dL)	57.88 ± 18.92	63.59 ± 17.27	0.402
LDL-Cal (mg/dL)	101.85 ± 31.34	116.22 ± 31.06	0.110
AST (U/L)	27.24 ± 12.01	26.82 ± 13.50	0.359
ALT (U/L)	20.67 ± 9.32	21.29 ± 12.68	0.593
eGFR (mL/min/1.73 m^2)	64.83 ± 19.44	65.24 ± 18.94	0.849
CBC
Hemoglobin (g/dL)	13.21 ± 1.76	12.84 ± 1.25	0.200
RBC count (×10^6/µL)	4.60 ± 0.62	4.49 ± 0.48	0.404
WBC count (×10^3/µL)	6.91 ± 1.65	7.63 ± 1.48	0.195
Lifestyle
Smoking, (%)
Nonsmoker	18 (75.0)	19 (79.2)	0.598
Ex-smoker	5 (20.8)	5 (20.8)
Current smoker	1 (4.2)	0 (0)
Drinking alcohol, (%)
Nondrinker	19 (79.2)	19 (79.2)	0.574
Ex-drinker	4 (16.7)	5 (20.8)
Occupation type, (%)
Indoor	22 (91.7)	21 (87.5)	0.637
Outdoor	2 (8.3)	3 (12.5)
Vegetarian, (%)
Yes	1 (4.2)	0 (0.0)	0.312
No	23 (95.8)	24 (100.0)
Chemical, (%)
Yes	0 (0.0)	1 (4.2)	0.312
No	24 (100.0)	23 (95.8)

BMI = body mass index, BUN = blood urea nitrogen, HDL-Chol = high density lipoprotein-cholesterol, LDL-Cal = calculated low density lipoprotein cholesterol, AST = aspartate aminotransferase, ALT = alanine aminotransferase, eGFR = estimated glomerular filtration rate, CBC = complete blood count, RBC = red blood cell, and WBC = white blood cell. Data are presented as the mean ± SD. The statistical significance of differences in categorical variables data was evaluated by chi-square test (a); nonparametric variables were analyzed by the Mann-Whitney test (b) and parametric variables by unpaired Student’s -test (c).