Research Article

Higher Urinary Levels of 8-Hydroxy-2′-deoxyguanosine Are Associated with a Worse RANKL/OPG Ratio in Postmenopausal Women with Osteopenia

Table 2

Simple correlation between 8-OHdG and RANKL, OPG and RANKL/OPG, BMD values, and bone resorption/formation markers (total sample, ).

8-OHdG

L. spine BMD−0.13
F. neck BMD0.04
Total hip BMD0.03
CTX-10.07
BAP0.06
RANKL0.263
OPG−0.116
RANKL/OPG0.277

by Pearson’s analysis of base-10 logarithm transformed values of the 2 variables.
BMI: body mass index; BMD: bone mass density; L.: lumbar; F.: femoral; CTX-1: C-terminal telopeptide of type I collagen; BAP: bone-specific alkaline phosphatase; OPG: osteoprotegerin; RANKL: receptor activator of nuclear factor kappa-B ligand; 8-OHdG: 8-hydroxy-2′-deoxyguanosine.