Correlation of Oxidative and Antioxidative Processes in the Blood of Patients with Cervical Spinal Cord Injury

Table 3

Concentrations of lipid peroxidation products: thiobarbituric acid reactive substances (TBARS) and conjugated dienes (CD); activities of antioxidant enzymes: superoxide dismutase (SOD), glutathione peroxidase (GPx), and catalase (CAT); concentration of reduced glutathione (GSH), as well as creatine kinase (CK) activity in healthy volunteers (Control I), patients with cerebral concussion (Control II), and patients with injured cervical part of the spinal cord before and 7days after the surgery (studied group).

Parameters	Healthy volunteers; (Control I)	Patients with cerebral; concussion (Control II)	⁢Studied group
			Before the surgery	7 days after the surgery
TBARS in blood plasma (nmol MDA/mL)	0.28 ± 0.06	0.43 ± 0.04	0.62 ± 0.01	0.41 ± 0.05
TBARS in erythrocytes (nmol MDA/g Hb)	24.9 ± 2.6	33.7 ± 3.9	45.7 ± 5.7	32.7 ± 5.5
CD in blood plasma (Abs./mL)	0.34 ± 0.03	0.56 ± 0.12	0.77 ± 0.24	0.44 ± 0.15
CD in erythrocytes (Abs./g Hb)	1.94 ± 0.26	2.67 ± 0.67	3.48 ± 0.94	2.14 ± 0.53
SOD (U/g Hb)	1190.6 ± 106	1065.8 ± 160.1	997.6 ± 109.4	1243.7 ± 221
CAT (10^4 IU/g Hb)	41.5 ± 4.3	59.4 ± 9.7	69.9 ± 13.1	49.3 ± 8.3
GPx (U/g Hb)	13.6 ± 1.7	20.9 ± 6.1	21 ± 7.8	14.2 ± 4.8
GSH (10^−3 μmol)	11.1 ± 2.1	10.9 ± 3.8	11.9 ± 3.2	10.6 ± 4.1
CK (IU/L)	15.2 ± 1.6	29.7 ± 2.8	30.7 ± 3.5	20.3 ± 2.6

The values are expressed as means ± standard deviations (SD) of the means. Statistically significant differences: versus before the surgery: ; versus Control I: , , and ; versus Control II: , , and .