Research Article
Isosteviol Sensitizes sarcKATP Channels towards Pinacidil and Potentiates Mitochondrial Uncoupling of Diazoxide in Guinea Pig Ventricular Myocytes
Figure 2
STV increased the amplitude and activating rate of pinacidil-induced current. (a) Representative pinacidil-induced currents of STV-preincubated (10 μM) and control group. (b) Effect of 10 μM STV on current-voltage () relationship of pinacidil-induced channel current. Currents were normalized to cell capacitance. (c) The time course of channel activation by pinacidil for STV-preincubated and control group. (d) Comparison of activation rates of channel between STV-preincubated and control group. means .
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