Oxidative Stress Biomarkers and Left Ventricular Hypertrophy in Children with Chronic Kidney Disease

Table 2

Selected parameters depending on CKD stage in the investigated group of 65 patients.

Parameter	CKD stage				value
	1 + 2; ()	3; ()	4; ()	5; ()
hsCRP (ng/mL)	171.6; (128.7; 464.3)	252.4; (106.5; 2574.9)	338.9; (143.0; 771.6)	365.6; (187.2; 878.1)	0.397
Carbonyl groups (nmol/mg)	1.15; (0.54; 1.32)	1.24; (0.87; 1.69)	1.64; (0.73; 2.41)	1.23; (0.66; 2.05)	0.454
oxLDL (U/L)	80.65; (60.56; 109.68)	75.81; (56.66; 97.87)	82.31; (75.48; 91.92)	98.89; (82.16; 108.73)	0.030
Aldosterone (pg/mL)	186.1; (103.5; 298.7)	272.8; (142.3; 662.1)	471.00; (169.0; 1073.1)	192.3; (86.4; 711.4)	0.250
PRA (ng/mL/h)	4.99; (1.25; 8.38)	6.88; (3.41; 12.51)	4.69; (1.64; 9.98)	3.88; (2.01; 7.94)	0.521
ICAM-1 (ng/mL)	305.7; (289.4; 354.3)	319.1; (291.8; 446.3)	322.1; (290.3; 337.7)	329.2; (267.3; 408.9)	0.922
Insulin (μIU/mL)	9.0; (7.0; 10.6)	9.5; (8.1; 15.7)	12.8; (10.1; 16.8)	13.1; (6.9; 16.3)	0.162
Albumin (g/L)	45.0; (41.0; 47.0)	45.50; (41.0; 47.5)	46.8; (45.0; 49.1)	44.1; (37.7; 47.1)	0.127

Values presented as median (25th–75th percentile)
hsCRP—high sensitive C-reactive protein; oxLDL—oxidized low-density lipoprotein; PRA—plasma renin activity; ICAM-1—intercellular adhesion molecule-1.
Statistically significant differences between stages 3 and 5.