Cholesterol Retards Senescence in Bone Marrow Mesenchymal Stem Cells by Modulating Autophagy and ROS/p53/p21^Cip1/Waf1 Pathway

Figure 1

The detection of senescence-associated phenotype in BMSCs at the 1st (P1) and 2nd (P2) and 3rd passage (P3). (a) Representative image of β-galactosidase (SA-β-gal) staining in BMSCs at P1, P2, and P3. (b) Percentage of SA-β-gal positive senescent cells in BMSCs at P1, P2, and P3. (c) and (d) Expression levels of p53 and proteins in BMSCs at P1 and P3. Data are expressed as mean ± SD, for each group, , versus P1.

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