Cholesterol Retards Senescence in Bone Marrow Mesenchymal Stem Cells by Modulating Autophagy and ROS/p53/p21^Cip1/Waf1 Pathway

Figure 3

Effects of CH on expression of p53, , and LC3 proteins. (a) and (b), Expression of p53 protein in the P3 or in the P1 with H₂O₂ (25 μM, 6 h). for each group, , versus Ctl group; , versus H₂O₂ group. (c) and (d) Expression of proteins in the P3 or in the P1 cells treated with H₂O₂. for each group, , versus Ctl group; , versus H₂O₂ group. (e) Expression of LC3 protein in BMSCs with or without different concentrations of CH. for each group, versus P1 group; , versus P3.

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