Research Article
Sociodemographic and Lifestyle Determinants of Plasma Oxidative Stress Markers 8-OHdG and F2-Isoprostanes and Associations with Metabolic Syndrome
Table 1
Sample and subject characteristics (
) of participants with plasma 8-OHdG and/or F2-isoprostane measurement.
| | | Mean (SD) or % |
| | Sociodemographics | | | Age (years) | 42.5 (14.1) | | Female | 64.7% | | Education (years) | 12.7 (3.2) | | North-European ancestry | 96.6% |
| | Lifestyle | | | Smoking | | | None (never/former) | 69.3% | | 10 cig/day | 14.8% | | 10 cig/day | 15.9% | | Plasma cotinine ng/mL | 71.2 (175.9) | | Alcohol | | | ♂/♀ < 1 units/wk | 23.2% | | ♂ ≤ 21/♀ ≤ 14 units/wk | 65.0% | | ♂ > 21/♀ > 14 units/wk | 11.8% | | Physical activity (MET-min/wk) | 3742 (3072) | | Body mass index (BMI) (kg/m2) | 25.3 (4.5) | | Supplement users | 11.5% |
| | Metabolic, health, and disease factors | | | Waist circumference (cm) | 88.5 (13.4) | | Triglycerides (mmol/liter) | 1.3 (0.9) | | HDL-cholesterol (mmol/liter) | 1.6 (0.4) | | LDL-cholesterol (mmol/liter) | 3.1 (1.0) | | Fasting glucose (mmol/liter) | 5.2 (0.9) | | Systolic blood pressure (mmHg) | 137 (20) | | Diastolic blood pressure (mmHg) | 81 (11) | | Metabolic syndrome (MetS) | 19.6% | | of MetS components | 1.4 (1.3) | | chronic diseases | | | 0 | 62.3% | | 1 | 26.6% | | 2 or more | 12.1% | | Cardiometabolic (cardiovascular disease, diabetes) | 8.7% | | Musculoskeletal (osteoarthritis, rheumatic disorders) | 9.4% | | Chronic nonspecific lung disease | 6.5% | | Cancer | 3.3% |
| | Sampling variables | | | Season at time of sample collection | | | Winter (Dec.–Feb.) | 20.3% | | Spring (Mar.–May) | 24.5% | | Summer (Jun.–Aug.) | 24.5% | | Autumn (Sep.–Nov.) | 30.6% | | Fasting prior to sample collection | 95.6% |
| | Oxidative stress markers | | | 8-Hydroxy-2′-deoxyguanosine (8-OHdG) (pmol/liter) | 45.5 (17.0) | | F2-isoprostanes (pmol/liter) | 120.6 (40.4) |
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Cig: cigarettes; HDL: high-density lipoprotein; LDL: low-density lipoprotein; : number; MET: metabolic equivalent of task; MetS: metabolic syndrome; Wk: week.
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