Effects of Epigallocatechin Gallate on Tert-Butyl Hydroperoxide-Induced Mitochondrial Dysfunction in Rat Liver Mitochondria and Hepatocytes

Table 1

Respiratory control ratio.

Treatment	Control	EGCG2	EGCG10	EGCG50	tBHP0.25	EGCG2 + t-BHP0.25	EGCG10 + tBHP0.25	EGCG50 + tBHP0.25
Mit	11.6 ± 1.3	10.5 ± 1.1	10.0 ± 0.9	7.0 ± 1.1	6.3 ± 0.9	5.8 ± 0.7	5.9 ± 0.2	4.4 ± 0.3
Hep	5.5 ± 1.1	5.1 ± 1.0	5.2 ± 0.8	4.2 ± 0.6	3.3 ± 0.5	3.2 ± 0.6	3.3 ± 0.6	2.7 ± 0.5

Data are expressed as the mean ± standard deviation. Mit = mitochondria and Hep = permeabilized hepatocytes. Concentration of tBHP is shown in mmol/L and that of EGCG in mol/L; versus control, + versus corresponding EGCG, and # versus tBHP alone; , <0.01, or <0.001 for one, two, or three symbols, respectively; = 6–10.