Kaempferol Attenuates Myocardial Ischemic Injury via Inhibition of MAPK Signaling Pathway in Experimental Model of Myocardial Ischemia-Reperfusion Injury

Figure 1

Effect of KMP on arterial pressure and ventricular function. (a) SAP; (b) MAP; (c) DAP; (d) HR; (e) maximal positive rate of the left ventricular pressure (+LVdP/); (f) maximal negative rate of the left ventricular pressure (−LVdP/); (g) LVEDP. IR-C: ischemia-reperfusion control; KMP 20 + IR: kaempferol 20 mg/kg/day + ischemia-reperfusion; KMP 20 ps: kaempferol 20 mg/kg/day per se. Data are expressed as the mean ± SEM; in each group versus sham; , , and versus IR-control.

(a)

(b)

(c)

(d)

(e)

(f)

(g)