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Oxidative Medicine and Cellular Longevity
Volume 2016, Article ID 7857186, 17 pages
Review Article

Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician’s Expectation Be Matched by the Reality?

School of Human Movement and Nutrition Science, The University of Queensland, Brisbane, Australia

Received 13 October 2015; Accepted 6 December 2015

Academic Editor: Ahmed Abdel Moneim

Copyright © 2016 Christine A. Houghton et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

The following supplementary material illustrates sulforaphane’s chemical structure, synthesis and interactivity, together with its effects on gene expression in key pathways.

Table 1: Major Products of Nrf2 Target Genes

Figure 1: Molecular structure of sulforaphane

Figure 2: Sulforaphane synthesis via myrosinase enzyme

Figure 3: Epithiospecifier protein, an inhibitor of myrosinase enzyme

  1. Supplementary Material