Oxidative Stress and Liver Cancer: Etiology and Therapeutic Targets

Table 1

Summary of HCC patients with oxidative DNA damage and inflammation markers.

Ref number	Damage factors	Inflammation markers
[5]	HBV, HCV, NASH	IL-6
[6, 7]	HBV, HCV, NASH	TNF-α
[8]	HBV, HCV, NASH	TGF-β, H2O2, NO
[13]	Mitochondrial dysfunction	p53
[14]	NASH	CYP2E1
[17, 18]	HBV, HCV	RASSF1A, GSTP1, CHRNA3, DOK1
[27]	HBV, HCV, NASH	cfDNA
[28, 29]	HBV, HCV, NASH	miRNA
[30]	HBV, HCV, NASH	miRNA-199a, miR-199b, miR-122a, miR-92, miR-222
[31]	HBV, HCV, NASH	NF-kB, OxLDL
[32–35]	NASH	IL-17
[36–47]	NASH	Adiponectin
[48]	NASH	Sulfatase 2
[49–51]	NASH	Adiponectin
[52]	HBV	IL-1β, IL-6, CXCL-8, TNF-α
[53–55]	HBV	HBx
[56]	HCV	PD-L1
[57]	HBV, HCV	8-OHdG
[58, 59]	HCV	Fe^2+