Endogenous n-3 Fatty Acids Alleviate Carbon-Tetrachloride-Induced Acute Liver Injury in Fat-1 Transgenic Mice

Table 4

Effects of endogenous omega-3 fatty acids on oxidative stress parameters in the liver.

Parameters	WT	WT/CCl4	Fat-1/
MDA (nmol/mg protein)	2.52 ± 0.34	4.73 ±	3.99 ±
SOD (U/mg protein)	303.8 ± 33.8	214.3 ±	261.8 ±
CAT (U/mg protein)	13.5 ± 1.9	7.52 ±	9.97 ±
GSH-Px (U/mg protein)	975.6 ± 317.2	565.4 ±	770.1 ±
GR (U/g protein)	10.6 ± 1.7	6.22 ±	7.92 ±
GSH (mg/g protein)	11.6 ± 1.8	7.96 ±	9.27 ±
GSSG (mg/g protein)	1.26 ± 0.36	2.29 ±	1.72 ±
GSH/GSSG (fold)	9.72 ± 2.27	3.62 ±	5.46 ±

Data are expressed as mean ± SD (). and versus WT group; and versus WT/CCl₄ group.