Research Article

Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model

Table 1

Summary of the effect on HeLa cell of CDDP, α-M, and their combinations in the preincubation scheme. The table presents the combination index (CI) calculated based on the equation given in the text. Mean values of three separate experiments performed in triplicate.

Drugs in combinationDrugs aloneControl growth Combination indexInteraction
CDDP μM (D1)α-M μM (D2)CDDP μM ()α-M μM ()

256.68.489.81.1
21020.713.873.00.8Synergistic
51025.414.868.01.0Additive
21537.916.556.11.0Additive