Research Article

Synergic Effect of α-Mangostin on the Cytotoxicity of Cisplatin in a Cervical Cancer Model

Table 2

Cell cycle analysis after treatment with α-M, CDDP, and the combined treatments using both the coincubation and preincubation schemes. Values are the mean ± SD of three independent experiments for each point.

GroupsG1/G0SG2/MG2/G1 ratio

Coincubation
Control
CDDP 2 μM
α-M 10 μM
α-M 15 μM
CDDP+α-M (2/10 μM)
CDDP+α-M (2/15 μM)

Preincubation
Control
CDDP 2 μM
α-M 10 μM
α-M 15 μM
CDDP+α-M (2/10 μM)
CDDP+α-M (2/15 μM)

versus control group.