Interplay between Superoxide Dismutase, Glutathione Peroxidase, and Peroxisome Proliferator Activated Receptor Gamma Polymorphisms on the Risk of End-Stage Renal Disease among Han Chinese Patients

Table 2

Comparisons of the minor allele frequencies of the four SNPs and examinations of the Hardy-Weinberg equilibrium among the entire cohort.

SNPs	rs #	Nucleotide Change (amino acid change)	Location	Controls ( = 780)		Cases ( = 671)
				MAF	HWE value	MAF	HWE value
SOD2	rs4880	T → C; (Val → Ala)	exon 2	13.97%	0.768	17.36%	0.423
GPX1	rs1050450	C → T; (Pro → Leu)	exon 2	5.38%	0.720	5.29%	0.249
P12A	rs1801282	C → G; (Pro → Ala)	exon B	3.08%	0.526	4.99%	0.020
C161T	rs3856806	C → T; (His → His)	exon 6	24.29%	0.697	26.53%	0.488

HWE = Hardy-Weinberg equilibrium.
MAF = minor allele frequency.