Research Article
Interplay between Superoxide Dismutase, Glutathione Peroxidase, and Peroxisome Proliferator Activated Receptor Gamma Polymorphisms on the Risk of End-Stage Renal Disease among Han Chinese Patients
Table 6
Multivariate analysis of the predictors of dialysis by fitting multiple logistic regression model with the stepwise variable selection method, including SOD2, GPX1, and PPAR- polymorphisms#.
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Multiple logistic regression model: = 1451, adjusted generalized = 0.304, estimated area under the receiver operating characteristic (ROC) curve = 0.769, and the Hosmer and Lemeshow goodness-of-fit chi-square test = 0.0047 (df = 8). #Variables with odds ratio (OR) of extreme values were listed below: DM × SOD2 exon 2 CC, OR 2.7 × 106 ( < 0.001); non-DM × PPAR-γ exon B GG, OR 3.8 × 1013 ( < 0.001); PPAR-γ exon 6 TT × PPAR-γ exon B GG, OR 8.2 × 1011 ( < 0.001); GPX1 exon 2 CC × PPAR-γ exon B GG, OR 1.9 × 10−7 ( < 0.001). |