Properties of Flavonoids Isolated from the Bark of Eysenhardtia polystachya and Their Effect on Oxidative Stress in Streptozotocin-Induced Diabetes Mellitus in Mice
Table 5
Antioxidative status of mice and biochemical parameters at the end of the experimental period.
Organ
Group
SOD
CAT
CSH-Px
GSH
MDA
(U/min−1)
(U/s−1)
(U/mL−1)
(U/mL−1)
(nmol/mL−1)
Kidney
N
2.2 ± 0.34
0.74 ± 0.005
68.65 ± 2.43
25.27 ± 4.31
29.12 ± 3.57
MD
2.8 ± 0.26
0.59 ± 0.002
56.41 ± 5.19
5.29 ± 1.84
25.60 ± 5.16
MD + 1
3.6 ± 0.34
0.79 ± 0.005
71.65 ± 6.73
16.21 ± 1.53
27.93 ± 4.52
MD + 2
3.1 ± 0.39
0.76 ± 0.006
67.62 ± 4.10
13.07 ± 3.76
26.62 ± 1.47
MD + 3
3.7 ± 0.39
0.82 ± 0.006
73.80 ± 6.14
17.23 ± 1.95
28.18 ± 3.52
MD + 4
3.8 ± 0.42
0.84 ± 0.009
79.37 ± 4.42
19.87 ± 2.25
29.14 ± 5.32
MD + 5
3.7 ± 0.39
0.82 ± 0.004
74.26 ± 5.28
19.01 ± 4.78
28.01 ± 4.11
Liver
N
6.5 ± 0.18
0.82 ± 0.011
99.41 ± 6.16
48.76 ± 4.84
26.35 ± 4.25
MD
5.8 ± 0.13
0.58 ± 0.005
39.34 ± 5.63
26.48 ± 2.60
23.78 ± 2.17
MD + 1
6.2 ± 0.72
0.71 ± 0.006
79.59 ± 3.54
40.63 ± 3.62
25.77 ± 2.83
MD + 2
6.0 ± 0.28
0.65 ± 0.004
51.24 ± 6.10
35.89 ± 4.29
24.21 ± 4.76
MD + 3
6.3 ± 0.51
0.73 ± 0.003
90.21 ± 3.29
44.21 ± 7.36
26.53 ± 2.80
MD + 4
6.4 ± 0.73
0.79 ± 0.005
93.26 ± 5.17
47.02 ± 5.42
27.91 ± 5.52
MD + 5
6.1 ± 0.45
0.76 ± 0.002
89.38 ± 6.35
44.32 ± 6.15
27.22 ± 5.16
Pancreas
N
4.03 ± 0.37
0.74 ± 0.007
359.56 ± 4.67
51.26 ± 3.35
28.56 ± 5.42
MD
2.90 ± 0.67
0.65 ± 0.003
325.39 ± 6.23
19.48 ± 1.84
24.21 ± 3.43
MD + 1
3.70 ± 0.49
0.72 ± 0.004
342.29 ± 4.67
43.17 ± 3.27
26.55 ± 2.67
MD + 2
3.06 ± 0.30
0.69 ± 0.005
330.56 ± 7.52
30.84 ± 5.63
25.19 ± 6.54
MD + 3
3.80 ± 0.59
0.73 ± 0.005
346.99 ± 6.43
45.80 ± 3.52
26.56 ± 2.90
MD + 4
3.89 ± 0.47
0.75 ± 0.008
350.48 ± 5.39
47.22 ± 5.42
27.84 ± 4.53
MD + 5
3.12 ± 0.62
0.76 ± 0.009
349.14 ± 5.84
45.74 ± 6.21
27.18 ± 5.84
Each value represents the mean ± SEM from 6 rats. Values within columns bearing the same lower case letters (a, b, c, and d) are not different at and are not in any particular order. Normal control (N) and diabetic control (MD).
