Review Article

Bioactivity of Polyphenols: Preventive and Adjuvant Strategies toward Reducing Inflammatory Bowel Diseases—Promises, Perspectives, and Pitfalls

Table 2

Selected food items rich in various polyphenol classes, including potential health beneficial effects.

Food itemEdible partConcentration (mg/100 g)Major polyphenol (classes)Reference regarding contentSuggested health effects, selectionReference regarding health effect

ApplesPeel50–120Phlorizin, phenolic acids: chlorogenic acid, quercetin[41]Blood glucose lowering, anti-inflammatory, lowering colonic inflammation[4244]
Flesh0.2–0.9
Totalca. 5–50

BlackberriesWhole130–405Anthocyanins, flavanols: EC, phenolic acid: ellagic acidPhenol explorer1Anti-inflammatory, anti-IBD[45, 46]

Blueberries, highbushWhole160–480Anthocyanins, flavonols: quercetin, phenolic acids: chlorogenic acidPhenol explorerAnti-inflammatory, anti-IBD[47]

Cacao Bean, powder300–1100Flavanols: ECPhenol explorerAnti-inflammatory, against heart failure[48, 49]

Chestnut, rawWhole nut547–1960Hydroxybenzoic acids: gallic acid, ellagic acid, tanninsPhenol explorerAnti-inflammatory[50]

ChocolateDark150–425Flavanols: epicatechin, hydroxycinnamic acid: ferulic acidPhenol explorerReducing CVD, anti-inflammatory[51]

Cloves Seasoning, dried1200–17500 Hydroxyhenylpropenes: eugenol, acetyl eugenolPhenol explorerAnti-inflammatory, antiulcer[52]

Coffee Beverage, filtered90Phenolic acids: chlorogenic acidPhenol explorerImproved blood lipids, improved glucose handling, anti-inflammatory but increases IBD symptoms[53, 54]

CurcumaSpice, whole200+Curcuminoids, flavonoids, phenolic acids[55]Anti-IBD, anticancerogenic, anti-inflammatory[56]

GrapefruitFlesh15–115Flavonoids, phenolic acidsPhenol explorerAnti-inflammatory[57]

Green teaDrinkable extract29–103Flavanols: EC, EGCGPhenol explorerAnti-inflammatory, anticolitic[58]

Olive oil, extra virginWhole oil4–200Tyrosols, lignans: pinoresinol; phenolic acids, hydrolysable tannins Phenol explorerAnti-inflammatory, reducing CVD[59]

Paprika, greenWhole fruit0.3–10Flavonoids: luteolin glucosides; hydroxycinnamic acids Phenol explorerAnti-inflammatory[60]

PeppermintSeasoning, dried450–26000Flavonoids: eriocitrin; hydroxycinnamic acids: rosmarinic acidPhenol explorerAnti-inflammatory[61]

PomegranateJuice240Punicalagin (an ellagitannin)[62]Anti-inflammatory, anti-IBD[63]

PotatoPeel
Flesh
180–5000#
1–1000#
Phenolic acids: chlorogenic acid [64]Glycoalkaloids may increase IBD, anthocyanins anti-inflammatory effects in colored potatoes[65, 66]
Total10–50Phenol explorer

Plum, darkTotal130–240Phenolic acids: chlorogenic acid; procyanidins, anthocyaninsPhenol explorerAnti-inflammatory, antioxidant [67, 68]

Red wineFinal product25–300Phenolic acids, anthocyanins, tannins, stilbenes (resveratrol)Phenol explorerImproved blood lipids, anti-inflammatory, anti-IBD [69, 70]

SoyFlour140–900Isoflavonoids: daidzein, glycitein, genistein, & glucosidesPhenol explorerImproved blood lipids, antiapoptotic effects, anti-inflammatory, anti-IBD[71, 72]

SpinachLeaf30–290FlavonolsPhenol explorerAnti-inflammatory, anti-IBD[73]

WheatWhole grain85–220Phenolic acids: hydroxybenzoic acids, hydroxycinnamic acidsPhenol explorerUnclear, enhancing celiac disease, controversial effects[74]

In juices and wine: mg/100 mL; 1http://phenol-explorer.eu/; #calculated from dry weight assuming 80% water content. Note that content in purple potatoes is ca. 5 times higher in polyphenol content than other varieties; concentration in mg/cm2, CVD = cardiovascular diseases, EC = epicatechin, and EPGC = epigallocatechin; +total polyphenols with Folin-Ciocalteu; effect refers to observation with whole food or respective extracts but is attributed—at least in part—to the respective polyphenols.