Effects of Astragalus Polysaccharides on Dysfunction of Mitochondrial Dynamics Induced by Oxidative Stress

Table 3

Fusion and fission-related genes mRNA expression in vitro.

	Control	t-BHP	Control + APS	t-BHP + APS
Mfn-1	1.00	0.88 ± 0.04	1.01 ± 0.12	0.95 ± 0.04
Mfn-2	1.00	0.88 ± 0.15	1.05 ± 0.02	0.99 ± 0.05
Opa-1	1.00	0.97 ± 0.05	1.00 ± 0.13	0.96 ± 0.18
Drp-1	1.00	1.12 ± 0.58	1.13 ± 0.37	1.06 ± 0.16
Fis-1	1.00	1.12 ± 0.49	1.04 ± 0.27	1.13 ± 0.19

Mfn-1: mitofusin 1; Mfn-2: mitofusin 2; Opa-1: optic atrophy 1; Drp-1: dynamin-related protein q; Fis-1: mitochondrial fission 1 protein. Significant difference between t-BHP and control groups (-test; ). Significant difference between t-BHP and t-BHP + APS groups (-test; ).