| | Reference | E group | C group | OS biomarkers lever | Cognitive test | Cognitive function | Relevance |
| | Sales et al., 2013 [96] | 14 male OSA | 13 male
subjects | Lower level of VitE, SOD, and VitB11 and higher homocysteine. Unchanged VitC, catalase, glutathione, and VitB12 level | WCST, the Digit Symbol Substitution Test, Digit Span, the Similarities Test, the Logical Memory and Verbal Paired Association Tests, and the Rey-Osterrieth Complex Figure Test | Worse attention, working memory, and verbal memory performance | Showing correlation between SOD, VitE, and cognitive function |
| | Li et al., 2014 [9] | 28 OSAS | 16 healthy adults | Significantly reduced serum SOD concentration and increased MDA concentration in OSAHS | MoCA | Delay recall, calculation, and language were impaired in OSAS | Serum SOD and MDA level were correlated with impaired neurocognitive function |
| | Li and Qin, 2007 [97] | 18 OSAS | 14 healthy adults | Increased serum NO concentration | WMS-RC,
WAIS-RC | Impaired memory (visual recognition and digit symbols) | The NO concentration was negatively related to cognitive function |
| | Huang et al., 2014 [98] | 41 OSAHS | 44 healthy adults | Higher Nox activity and serum 8-OHdG concentration in OSAHS | MMSE, MoCA | Impaired delay recall, attention, language, visual spatial, and executive function in OSAHS | Cognitive function was negatively associated with the Nox activity and serum 8-OHdG level |
| | Yang et al., 2013 [99] | 67 OSAHS | 20 healthy adults | Elevated AOPP, MDA and reduced SOD level in OSA patients | MMSE, ESS, and CDT | Impaired attention, calculation, and memory | AOPP, MDA, and SOD concentration were associated with the MMSE and CDT score |
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