Antidiabetic and Antinephritic Activities of Aqueous Extract of Cordyceps militaris Fruit Body in Diet-Streptozotocin-Induced Diabetic Sprague Dawley Rats

Figure 1

Diet-STZ-induced diabetic rats were treated with or without 100 mg/kg metformin (Met) and Cordyceps militaris water extract (CM) for four weeks. After the final drug treatment, the serum levels of insulin (a) and pyruvate kinase (b) were detected in all experimental rats. At the end of the experiment, after an oral treatment of 2 g/kg D-glucose in all experimental rats, the changes of plasma glucose (c) and area under the curve of glucose (d) were analyzed. Data are expressed as mean ± SEM () and analyzed using one-way ANOVA. and versus normal controls. and versus nontreated diabetic rats.

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