Figure 3: Diet-STZ-induced diabetic rats were orally treated with or without Met and CM at indicated doses for four weeks. The levels of IL-2 (a), IL-6 (b), TNF-α (c), and 6-keto-PGF (d) in serum were detected via ELISA method and histopathological changes in kidney collected from all experimental rats were observed through H&E staining (, ×400) (e). Data are expressed as mean ± SEM () and analyzed using one-way ANOVA. and versus control. and versus model group.