Functionalized Fullerene Increases NF-κB Activity and Blocks Genotoxic Effect of Oxidative Stress in Serum-Starving Human Embryo Lung Diploid Fibroblasts

Figure 4

F-828 affects proliferative activity of HELFs. (a) (FCA): (1): distribution of fluorescence intensities of the cells stained with PI; (2): shifts of the proportions of cells with an amount of DNA corresponding to the G1-, S-, and G2/M-phases of cell cycle depending on the F-828 concentration in the culture medium. (b) (FCA): (1): distribution of the cells treated with F-828 according to the FL1-Ki-67 signal strength; (2): dependence of the median values of the FL1-Ki-67 signals on the fullerene concentration. (c) (FCA): (1): distribution of the cells treated with F-828 according to the FL1-PCNA signal strength; (2): dependence of the median values of FL1-PCNA signals on the F-828 concentration.

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