Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized Rats

Table 3

Effects of TP on the mRNA levels of mtDNA-encoded subunits of complex I.

Subunits	Sham	GDX	GDX-0.5TP	GDX-1.0TP
ND1	0.78 ± 0.03	0.71 ± 0.04	0.74 ± 0.03^#	0.78 ± 0.04^##△
ND2	0.85 ± 0.04	0.84 ± 0.03	0.82 ± 0.04	0.86 ± 0.04
ND3	0.93 ± 0.04	0.91 ± 0.03	0.91 ± 0.05	0.92 ± 0.03
ND4	0.85 ± 0.05	0.72 ± 0.03	0.77 ± 0.06^#	0.85 ± 0.03^##△
ND4L	0.90 ± 0.04	0.89 ± 0.06	0.86 ± 0.06	0.91 ± 0.05
ND5	0.90 ± 0.05	0.88 ± 0.05	0.89 ± 0.05	0.91 ± 0.05
ND6	0.92 ± 0.05	0.90 ± 0.04	0.90 ± 0.05	0.92 ± 0.04

versus sham; ^# versus GDX; ^## versus GDX; ^△ versus GDX-0.5TP group.