Research Article

Rat Liver Enzyme Release Depends on Blood Flow-Bearing Physical Forces Acting in Endothelium Glycocalyx rather than on Liver Damage

Figure 3

Effects of calcium and addition of heparanase on endothelium glycocalyx and enzyme release by perfused isolated livers from PH rats. Results of enzyme activities are expressed as mean ± SE (six independent determinations per experimental point) of times over sham-operated (control) values for LDH, ALT, GDH, and OCT, after 24 h after surgery. To study the effect of heparanase III, this compound was injected via a side branch of the inflow cannula at a final concentration of 1.5 mU/mL.