Research Article

Mitochondrial Respiration in Human Colorectal and Breast Cancer Clinical Material Is Regulated Differently

Figure 7

(a) Dependences of normalized respiration rate values for HCC (dotted line), HBC (solid line), and healthy colon tissue samples (dashed line); double reciprocal Lineweaver–Burk plots. Samples from 32 patients with breast cancer and 10 patients with colorectal cancer were examined. (b) ADP-dependent respiration in healthy colon mucosa and smooth muscle tissue samples (Michaelis–Menten curve, ). Here, Vo and Vmax are rates of basal and maximal ADP-activated respiration, respectively.
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