Associations between Specific Redox Biomarkers and Age in a Large European Cohort: The MARK-AGE Project

Table 6

Associations of oxidative stress markers and antioxidants with age¹.

Compound	B	95% CI	r	r^2
(Constant)	59.13	56.79, 61.48			<0.001
Lycopene (μmol/L)	−2.783	−3.440, −2.126	−0.207	0.047	<0.001
Total cysteine (mol/L)	0.021	0.013, 0.029	0.133	0.020	<0.001
Uric acid (mg/L)	0.031	0.009, 0.054	0.071	0.004	0.005
Protein carbonyls (nmol/mg)	3.274	0.252, 6.296	0.054	0.003	0.034
3-Nitrotyrosine (pmol/mg)	0.094	0.004, 0.183	0.052	0.003	0.040

¹Multiple linear regression analysis with a forward approach to identify independent blood biomarkers with highest correlation to age; all biomarkers including ascorbic acid, glutathione, malondialdehyde, and α-tocopherol were assessed as covariates in the initial model; partial r and r²; , ().