Research Article

Acute Strenuous Exercise Induces an Imbalance on Histone H4 Acetylation/Histone Deacetylase 2 and Increases the Proinflammatory Profile of PBMC of Obese Individuals

Table 3

Systemic biomarkers in lean and obese individuals at rest and after strenuous exercise.

Time pointLeanObese

WBC (103/mm3)Rest6.45 ± 1.506.58 ± 2.59
Exercise8.32 ± 2.42a8.61 ± 3.21a
Cortisol (μg/dL)Rest19.61 ± 4.0531.02 ± 4.07b
Exercise22.91 ± 4.51a36.66 ± 2.38a,b
Leptin (pg/mL)Rest22.15 ± 7.9057.58 ± 14.33b
Exercise22.97 ± 8.4557.08 ± 11.26b
TBARS (nmol/mL)Rest1.65 ± 0.521.72 ± 0.37
Exercise2.45 ± 0.59a2.67 ± 0.48a
Protein carbonyl (nmol/mg protein)Rest1.25 ± 0.391.44 ± 0.43
Exercise1.67 ± 0.27a1.98 ± 0.36a,b
Total thiol (μmol/mL)Rest1.13 ± 0.211.18 ± 0.17
Exercise0.83 ± 0.19a0.78 ± 0.26a

Data presented as mean ± SD. aStatistical difference compared to rest values (). bStatistical difference between groups ().