Research Article

Acute Strenuous Exercise Induces an Imbalance on Histone H4 Acetylation/Histone Deacetylase 2 and Increases the Proinflammatory Profile of PBMC of Obese Individuals

Table 5

Correlation of H4ac status of LPS-stimulated PBMC and anthropometric, proinflammatory monocyte, and delta (Δ) value of TNF-α before and after exercise.

Levels of H4ac in LPS-stimulated PBMC (ng/mg of protein)
BeforeAfterΔ (after-before)

Body mass (kg)0.63 (0.01)0.57 (0.03)N.S.
BMI (kg/m2)0.63 (0.01)0.54 (0.04)N.S.
AC (cm)0.66 (0.01)0.55 (0.04)N.S.
WC (cm)0.57 (0.03)0.56 (0.03)N.S.
CD14+CD16+ (%)0.53 (0.05)N.S.N.S.
ΔTNF-αN.S.N.S.0.75 ()

Pearson’s Correlation presented as r ( value). values were considered significant when ≤0.05. AC: abdominal circumference; BMI: body mass index; TNF-α: tumour necrosis factor-alpha; WC: waist circumference; N.S.: nonsignificant correlation.