Exercise Training Restores Cardiac MicroRNA-1 and MicroRNA-29c to Nonpathological Levels in Obese Rats

Figure 8

Schematic representation of the effects of AET on obesity-induced pathological cardiac remodeling via the involvement of microRNA-1 and microRNA-29c. AET is a powerful stimulus modulating microRNA-1 and microRNA-29c that regulates their target genes (NCX1 and collagen), thereby counteracting the pathological CH phenotype.