Apolipoprotein CIII Overexpression-Induced Hypertriglyceridemia Increases Nonalcoholic Fatty Liver Disease in Association with Inflammation and Cell Death

Figure 4

Effects of apoCIII overexpression and high-fat diet consumption on the expression of genes related to lipid catabolism and secretion. mRNA expression levels for (a) ATGL, (b) CPT1, (c) UCP2, (d) PGC1α (d), (e) MTP, and (f) APOB100 in the livers of NTg and apoCIII mice fed either a low-fat (LF) or high-fat (HF) diets and normalized to β-actin ( = 6–8). Data are expressed as the mean ± SEM. versus HF group; versus CIII mice (; two-way ANOVA). values with nonmatching superscript letters are significantly different (; ANOVA followed by Bonferroni correction).

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